Abstract： Objective To evaluate the clinical efficacy of artificial dermis in treating traumatic wounds and to an-alyze the factors influencing the vascularization time of artificial dermis.Methods A prospective study was conducted on 130 patients with full-thickness skin defects due to trauma,treated at the Department of Repair and Reconstruction Sur-gery,Foshan Hospital of Traditional Chinese Medicine from January 2020 to May 2023.The clinical outcomes of artificial dermis treatment were assessed,and factors influencing dermal vascularization were analyzed using univariate ANOVA and multiple linear regression.Results All 130 patients had good wound healing,with an effective rate of 100％.The aver-age time for artificial dermal vascularization was(14.36±2.40)days.Multiple linear regression analysis showed that age,smoking,diabetes,and preoperative Bates-Jensen Wound Assessment Tool(BWAT)scores were significant factors influencing the time of dermal vascularization(P＜0.05).Conclusion Artificial dermis is effective in treating traumatic wounds.Age,smoking,diabetes,and preoperative BWAT scores are important factors influencing the vascularization time of artificial dermis.Clinicians should pay attention to elderly patients,encourage smoking cessation,control diet,and adopt targeted measures to promote rapid healing of wounds treated with artificial dermis.